"Petru Poni"
Institute of Macromolecular Chemistry

News SARS-CoV 2 News Staff Contact




Ongoing projects - testing
Only from ICMPP network
Project: Antitumoral Theranostic Platforms Based nn Carbon Dots and Polymer Matrices
Project status: Ongoing

Project: PN-III-P1-1.2-PCCDI-2017-0083
Acronym: TERADOT
Director partner PPIMC: Dr. Mariana PINTEALA
Duration: 2018 – 2020

The TERADOT consortium will implement this project with the aim of reaching its strategic objective: the consolidation of the consortium scientific and technical competencies (in particular those of the P3 partner with relaunch potential) in the field of econanotechnologies and advanced materials by supporting/ developing the existing research competences and the transferability of its research results. The TERADOT Consortium is an alliance that will devote its efforts to capitalize the potential of nanotechnologies by creating new teranostic platforms based on Carbon Dots (CDs) in order to radically change the proceedings to diagnose and treat cancer.

http://www.ch.tuiasi.ro/cercetare/proiecte/TERADOT/

Project: Design of novel beads chitosan/amidoximated starch for wastewater purification applications
Project status: Ongoing

Project: PN-III-P1-1.1-PD-2016-1313
Acronym: BEADCsAmOxS
Project manager: Dr. Diana Felicia LOGHIN
Duration: 2018 - 2021

This research project aims to develop novel ionic composites based on cross-linked chitosan (CS), as matrix, and poly(amidoxime) grafted on starch (AOSt), as entrapped chelating resin, prepared as beads, following an interdisciplinary approach. The obtained beads will be used for binding metal ions and dyes as a function of sorbent composition, synthesis strategy, pH, sorbent dose, temperature, initial concentration of metal ions and dyes, and contact time, respectively. To elucidate the mechanism of sorption of metal ions and dyes different isotherms and kinetic models will be applied. The resulted beads are expecting to show re-usability in sorption/desorption cycles with no significant decrease in sorption capacity.

https://beadcsamoxs.wordpress.com/

Project: Dynamic Constitutional Platforms for Targeted Drug Delivery
Project status: Ongoing

Project: PN-III-P1-1.1-TE-2016-1180
Acronym: DynaCoPlat
Project coordinator: Dr. Lilia CLIMA
Duration: 2018 – 2020

The next level in Drug Discovery is the easy building and self-generation of multifunctional nanostructures from commercially available or “easy to prepare” units, which will further self-assemble in a complex, tunable and multifunctional materials, suitable for very specific targeted drug delivery. In this regard, DynaCoPlat project’s main objective is to create dynamic nanoplatforms for developing dynamic systems for enhanced multivalent biorecognition with applications in targeted drug delivery. Project’s subject “the development of efficient nucleic acid targeted delivery systems” addresses the thematic priorities of the National Development Plan 2014-2020 programs (PN III) and Horizon 2020 strategy. The project will adopt modern synthetic pathways for preparing dynamic nanoplatforms with self-assembly properties based on dynamic chemistry and combinatorial methodology. The simplicity of the synthetic constitutional strategy using accessible and simple building blocks for facile self-generated nanoplatforms, presenting synergistic DNA and cell membrane affinities, can be considered as a valuable path toward the systematic discovery of active delivery systems. An important issue we aim to address is establishing a methodology for labelling of nanoplatforms with targeting molecules and achieve successful targeting property via introduction of selective cellular markers, thus increasing the efficacy and reducing the overall toxicity of therapeutic agents. On the other side, the STRATEGIC OBJECTIVE of DynaCoPlat project is the formation and consolidation of a young multidisciplinary team of researchers with complementary knowledge and experience, able to increase their scientific visibility and integration into scientific environment by publishing the results in high impact journals and application to competitions within the national and European Framework (H2020, Era-Net, Euronanomed, etc.).

http://www.intelcentru.ro/DynaCoPlat/home

Project: Eco-innovative technologies for recovering the platinum metal group from used catalytic converters
Project status: Ongoing

Project: PN-III-76PCCDI/2018
Acronym: ECOTECH-GMP
Responsible partner (ICMPP): Dr. Maria Cazacu
Duration: 2018-2020
Buget: 800000 Lei

Autocatalysts are used to convert vehicle exhaust (carbon monoxide, nitrogen oxides, hydrocarbons, etc.) into less harmful products, such as: carbon dioxide and nitrogen. Platinum group metals (PGMs) are the active component in autocatalysts and consequently the auto industry is the largest PGM consumer. Limited PGM resources demands recycling to support an expanding auto market. Traditional recycling methods are using high temperatures and highly oxidative agents (e.g. aqua regia) making them large energy consumers and environmental pollutants. As a result, there is a need to develop alternative ways to recycle PGMs with a significant decrease in energy consumption and a reduced impact on the environment. ECOTECH-GMP project at hand draws from the knowledge, skills and competences of top leading Romanian research institutions in materials science, physics, chemistry and engineering for creating the know-how to develop the eco-technologies required to recycle PGM with zero emissions. There is currently no such technology available in the world. Four sub-projects are proposed to solve the issue of PGM eco-recycling, encompassing electrochemistry, coordination chemistry, hydrodynamics and bioelectrochemistry. The sub-projects are intertwined and function in synergy to deliver several solutions to the issue at hand. The potential of this project is mesmerizing for any interested company: small initial capital, low energy consumption and high throughput. The benefits for the society at large are thrilling: improved public health because of decreased toxic pollutants (chlorides, nitrates, nitrides, etc.) and creating new jobs owing to the potential of this technology to transform into an industry.

http://www.3nanosae.org/ecotech-gmp-en/

Project: Engineered eco-friendly biocomposites with selective chelating properties for removal and recovery of heavy metal ions from contaminated waters
Project status: Ongoing

Project: PN-III-P1-1.1-TE-2016-1697
Acronym: Biocomp4MetIRem
Project manager: Dr. Maria Valentina DINU
Duration: 2018 - 2020

The project objective is to design novel ligand-functionalized biocomposites and to evaluate their performance and feasibility as selective sorbents for removal/recovery of heavy metal ions. The results obtained from modeling and optimization procedures using tools of artificial intelligence will provide very useful information for the experimental and industrial practice, in the sense of (i) substitution/prediction of experiments in order to save materials, energy, and time, as well as for a better planning of research activities, and (ii) emphasizing the maximum expected performance of a selected system and the conditions necessary to achieve it.

https://icmpp.ro/biocomp4metirem/

Project: Innovative nanotechnologies based on polymer for obtaining new advanced materials
Project status: Ongoing

Project: PNIII-40PCCDI
Acronym: NAPOLI  19
Responsible partner (ICMPP): Dr. Valeria Harabagiu
Duration: 2018-2020
Buget: 735000 Lei

The project is aimed at using the expertise that involved in consortium entities acquired in materials science. The consortium consists of three representative national institutes: INCD for Chemistry and Petrochemistry – ICECHIM Bucharest, INCD for Electrochemistry and Condensed Matter - INCEMC Timisoara and INCD of Chemical Pharmaceutical - ICCF Bucharest, and of two prestigious universities: University POLITEHNICA of Bucharest and the University of Bucharest and a remarkable institute of Romanian Academy: Institute of Macromolecular Chemistry – Petru Poni Iasi. Although having great tradition and noteworthy results, the first five institutions face a series of problems, from the lack of financial funds, equipment and the aging employees for ICCF and partly for INCEMC and ICECHIM, to the lack of highly qualified staff required for recent investments in equipment for all 5 institutions. In this respect, the project attempts relaunching the activity in the first 5 institutions of the consortium, by putting together the existing competencies, so as to develop new technologies in order to obtain new materials with high performance properties. Given that, 3 of the research teams are specialized in polymers (ICECHIM, Petru Poni and UPB) the developed technologies will use the polymers as intermediates or as a component in the finished product. To this end it is envisaged getting the titanium nitride for prosthetic coatings via inorganic-organic polymer nanocomposites, obtaining photocatalytic materials and antibacterial coatings by sol- gel reactions, obtaining of short-life or one-time use biomaterials from aliphatic polyesters and micro or nanocellulose and the development of new polyphase materials with medium or long life, based on biopolymers, through 3D printing. The project intends the full use of A1, A2, B and C checks in order to increase the institutional performance of partners.

Project: INNOVATIVE NANOTECHNOLOGIES BASED ON POLYMERS FOR NEW ADVANCED MATERIALS OBTAINING
Project status: Ongoing

Project:                                    PN-III-P1-1.2-PCCDI-2017-0428

Acronym:                                  NAPOLI19

Subproject responsible:            Dr. Tinca BURUIANÄ‚

 

Members in Project 2 (PC2): Eco-friendly nanostructured hybrid materials for surface protection against deterioration caused by microorganism and pollutants

Project 2 aims to produce smart coating materials that have advanced protection properties against the development of biofilms and deposit on surfaces such as stone, paper and metal. Metallic and/or inorganic nanoparticles coatings will be synthetized by sol–gel process using supercritical CO2, to achieve a minimal energy consumption and a manufacturing process with a low degree of pollution. Predictive models will be developed for antifungal and antibacterial properties, depending on the nature of nanoparticles that are included in the hybrid matrix. A series of tests will be carried out on the materials obtained, in order to validate biofilm prediction models with high biodegradability, under various environmental conditions.

Members in Project 3 (PC3)Biomaterials from aliphatic polyesters and micro- and nano-cellulosic modifiers for short-life and disposable products

This is a complex, multidisciplinary and innovative project, which aims to develop a new material, a bionanocomposite and a new synthesis method that can be easily scaled up. The biomaterial obtained within this project is intended for food or drugs packs, single-use medical instruments, medical sample storage containers, short-life or disposable products in large quantities that are difficult or impossible to recover. This project aims to replace petroleum-based polymers with recyclable polymers from renewable resources, to reduce the pollution caused by using plastic packaging.

https://icechim-rezultate.ro/proiect.php?id=36&lang=en

Project: Institutul de Chimie Macromoleculara “Petru Poni” - Pol interdisciplinar de specializare inteligenta prin cercetare-inovare si transfer tehnologic in (bio/nano)materiale polimere si (eco)tehnologii
Project status: Ongoing

Project: POC F; 142/10.10.2016
Acronym: InoMatPol
Project coordinator: Dr. Narcisa Laura MARANGOCI
Duration: 2016 - 2019

Obiectivul general al proiectului InoMatPol constă în creÅŸterea capacităţii, calităţii ÅŸi eficienÅ£ei activităţii CDI din ICMPP prin deschiderea de noi direcÅ£ii de cercetare ÅŸi diversificarea gamei de servicii de cercetare orientate în special către industrie – conform cerinÅ£elor de inovare ale agenÅ£ilor economici din cadrul structurilor de tip cluster, în scopul stimulării competitivităţii cercetării ÅŸtinÅ£ifice româneÅŸti la nivel european ÅŸi a competitivităţii economice naÅ£ionale/regionale ale Institutului ÅŸi ale actorilor economici în domeniul de specializare inteligentă eco-nano-tehnologii ÅŸi materiale avansate.

http://http://inomatpol.icmpp.ro/

Project: Integrated and sustainable processes of environmental pollution, wastewater reuse and waste recovery
Project status: Ongoing

Project: PN-III-P1-1.2-PCCDI-2017-0245, Contract 26PCCDI/1.03.2018
Acronym: SUSTENVPRO
Director partner PPIMC: Dr. Marcela MIHAI
Project Component 2 (PC2): Efficiency of water treatment processes and development of innovative materials for the elimination of priority pollutants
Duration: 2018 - 2020

The objective of PC2 is to improve some technologies in advanced drinking water treatment, objective that at European level represents a challenge for drinking water suppliers. Therefore, during the project, innovative polymeric materials or composites will be designed, with properties (porosity, shape, size, sorption capacity, selectivity) adapted to the characteristics of the treated waters (types and concentrations of pollutants), with high efficiency for eliminating priorities model pollutants studied in the SUSTENVPRO project.

http://sustenvpro.dimm.tuiasi.ro/

Project: Intelligent therapies for non-communicable diseases based on controlled release of pharmacological compounds from encapsulated engineered cells and targeted bionanoparticles
Project status: Ongoing

Project: PN-III-P1-1.2-PCCDI-2017-0697
Acronym: INTERA
Project Component 4 (PC4) coordinator: Dr. Mariana PINTEALA
PC4: Polymeric conjugates for efficient induction of expression of genes of interest with applicability in cell therapy
Duration: 2018 – 2020

The complex project INTERA aims to develop innovative therapeutic methods to ameliorate the pathological progression by reducing the inflammatory process. The multidisciplinary studies proposed by INTERA can create and define new nano- or micro-medical devices usable for smart and innovative anti-inflammatory therapies. INTERA includes 4 projects: (1) Encapsulation of genetically manipulated eukaryotic cells for controlled release of pharmacologically active products; (2) Development of a 3D platform designed for pre-clinical drug testing composed of cells incorporated into three-dimensional bio-matrices; (3) Intelligent nanobioparticles designed for specific targeting  of bioactive compounds to pathological sites to reduce (treat) vascular inflammation. (4) Polymeric conjugates to induce efficiently  the expression of genes of interest with applicability in cellular therapy.

http://www.icbp.ro/static/en/en-networking_grants-grants-national_grants/intera.html

Project: Intelligent therapies for non-communicable diseases, based on the controlled release of pharmacological compounds from cells encapsulated after genetic manipulation or vectorized bionanoparticles
Project status: Ongoing

Project:                                PN-III P1-1.2-PCCDI-2017-0697
Acronym:                              INTERA
Responsible partner (ICMPP): Dr. Gheorghe Fundueanu
Duration:                              2018-2020
Buget:                                   1,380,000 lei

    The INTERA complex project aims to develop innovative therapeutic methods that, by reducing the inflammatory process, will improve the pathological processes. INTERA includes multidisciplinary studies that only together can create and define new medical nano- or micro-devices that can be used for intelligent and innovative anti-inflammatory therapies. INTERA includes 4 projects: (1) Encapsulation of genetically manipulated eukaryotic cells for the controlled release of some pharmacologically active products (2) Creating a 3D platform designed for pre-clinical drug testing consisting of cells incorporated into three-dimensional bio-matrices; (3) Intelligent nanobioparticles designed for vectoring bioactive compounds to pathological sites for the therapy of vascular inflammation (4) Polymer conjugates for the efficient induction of expression of genes of interest with applicability in cell therapy. The consortium consists of 4 partner research units - two institutes of the Romanian Academy (IBPCNS, ICMPP), a university (UPB) and a national CD institute (INCDFM) with good territorial coverage (Bucharest-Ilfov-IaÈ™i).

http://www.icbp.ro/static/en/en-networking_grants-grants-national_grants/intera.html

Project: Laboratory of Supramolecular Chemistry for Adaptive Delivery Systems ERA Chair Initiative
Project status: Ongoing

Project: Horizon 2020 WIDESPREAD 2-2014: ERA Chairs, no: 667387
Acronym: SupraChem Lab
Project coordinator: Dr. Mariana PINTEALA / Project manager: Dr. Teodora RUSU
Duration: 2015 - 2020

Considering the “P Poni” Institute of Macromolecular Chemistry (PPIMC) development strategy and also the research challenges in the Romanian Smart Specialisation Strategy as well as the Horizon 2020 objectives it is vital to set up an optimal research team for the IntelCentre able to improve the excellence of the centre within PPIMC and in the European research and innovation landscape. It is very important to adjust the level of research carried out in the IntelCentre to the level of leading international laboratories and to position the Centre as forefront of Romanian research in this area.

The strategic objective of the SupraChem Lab Project is to unlock and foster excellent research in PPIMC IntelCentre by setting up a strong research group in the field of hybrid materials for adaptive self-organized supramolecular structures.

http://www.intelcentru.ro/suprachem_lab

Project: Lego-style approach for problematic water streams treatment
Project status: Ongoing

Project: 224-ERA.Net RUS Plus
Acronym: WaterLego
Director partner PPIMC: Dr. Marcela MIHAI
Duration: 2018 - 2020

The objective of the WATER-LEGO project is to generate innovative, accessible and environmentally friendly materials, which can be assembled in a "lego" style in the form of sequential sorption filters, for decontamination of waters containing mixtures of toxic or unconventional pollutants.

Project: Mimicking living matter mechanisms by five-dimensional chemistry
Project status: Ongoing

Project: PN-III-P4-ID-PCCF-2016-0050
Acronym: 5D-nanoP
Project coordinator: Prof. Aatto LAAKSONEN
Duration: 2018 – 2022

 Mimicking of the living matter mechanism of cooperation by complementarity represents one of the most challenging tasks of supramolecular chemistry. The momentary solution consists in using particularly designed molecular unimers, endowed with the necessary amount of chemical information.

The 5D-nanoP project is dedicated to interfacing the fundamental research area of constitutional dynamic chemistry with the practical approaches of medicinal chemistry and biomedical applications. In the spirit of a metaphor of Jean-Marie Lehn (Nobel Prize in Chemistry, 1987), the project aims to materialize the concept of 5D chemistry in designing, synthesizing, characterizing, and using molecules with conditional affinity, to build versatile supramolecular nanoplatforms able to vectorize compounds of pharmaceutical or biochemical relevance, all of them involved in physiologic and pathologic processes at cell- and tissue-level.

http://www.intelcentru.ro/5D-nanoP/

Project: Mimicking living matter mechanisms by five-dimensional chemistry approaches
Project status: Ongoing

Project: PN-III-P4-ID PCCF-2016-0050
Acronym: 5D-nanoP
Responsible partner (P2): Dr. Ioan Cianga
Duration: 2018-2022
Buget: 945,000 lei

The 5D-nanoP project aims to interface the fundamental scientific field of constitutional dynamic chemistry with the practical approaches of medical chemistry and biomedical applications. In the spirit of the metaphor launched by Jean-Marie Lehn (Nobel Prize for Chemistry, 1987), the project proposes to materialize the concept of 5D chemistry by designing, synthesizing, characterizing and using molecules with conditioned affinity, for the development of supramolecular nanoplatforms, useful as pharmacological and genetic vectors implicated in physiological or pathological processes at the cellular and tissue level.

http://www.intelcentru.ro/5D-nanoP/ro/

Project: Mimicking living matter mechanisms by five-dimensional chemistry approaches
Project status: Ongoing

Project:                            PN-III-P4-ID PCCF-2016-0050
Acronym:                          5D-nanoP
Responsible partner (P3):  Dr. Gheorghe Fundueanu
Duration:                          2018-2022
Buget:                               945,000 lei

    The 5D-nanoP project aims to interface the fundamental scientific field of constitutional dynamic chemistry with the practical approaches of medical chemistry and biomedical applications. In the spirit of the metaphor launched by Jean-Marie Lehn (Nobel Prize for Chemistry, 1987), the project proposes to materialize the concept of 5D chemistry by designing, synthesizing, characterizing and using molecules with conditioned affinity, for the development of supramolecular nanoplatforms, useful as pharmacological and genetic vectors implicated in physiological or pathological processes at the cellular and tissue level.

http://www.intelcentru.ro/5D-nanoP/ro/

Project: Mimicking living matter mechanisms by five-dimensional chemistry approaches
Project status: Ongoing

Project: PN-III-P4-ID PCCF-2016-0050
Acronym: 5D-nanoP
Responsible partner (ICMPP – P4): Dr. Maria Cazacu
Duration: 2018-2022
Buget: 945,000 Lei

The 5D-nanoP project aims to interface the fundamental scientific field of constitutional dynamic chemistry with the practical approaches of medical chemistry and biomedical applications. In the spirit of the metaphor launched by Jean-Marie Lehn (Nobel Prize for Chemistry, 1987), the project proposes to materialize the concept of  5D chemistry by designing, synthesizing, characterizing and using molecules with conditioned affinity, for the development of supramolecular nanoplatforms, useful as pharmacological and genetic vectors implicated in physiological or pathological processes at the cellular and tissue level.

http://www.intelcentru.ro/5D-nanoP/ro/

Project: Multifunctional Spin Crossover Materials
Project status: Ongoing

Project: H2020-MSCA-RISE-2016, Cod proiect:734322
Acronym: SPINSWITCH
Responsible partner (ICMPP): Dr. Sergiu Shova
Duration: 2017-2021
Buget: 90000 Euro

This project deals with an exchange programme of seven research teams with the aim to establish and consolidate a network for the design of innovative multifunctional materials based upon iron(II) spin crossover complexes: their synthesis, magnetic and spectroscopic studies, investigations on their crystalline, liquid crystalline and morphological structures, pressure effects on spin crossover properties and, particularly, their implementation into pressure sensors. The synthetic part of this project aims to access novel types of crystalline and liquid crystalline spin crossover complexes, hybrid luminescent materials, photo-switchable liquid crystalline compounds, composites and nano- objects of original morphologies and transition characteristics. These switchable materials will become a matter of different experiments under pressure: magnetic and MÓ§ssbauer measurements under hydrostatic pressure and optical experiments in a gas pressure cell. This will allow to reach an important impact on the synthesis of new bistable materials, on their behaviour under pressure, and to make them an active part of different pressure sensors. The academic participants involved in this work have collaborated on joint projects and have co-authored several scientific papers. The two industrial institutions have a recognized expertise in organic and material synthesis, commercialization, as well possessing experience on elaboration of spin transition materials. The establishment of this joint exchange programme will promote and strengthen the complementarity of the participants and will stimulate cross-fertilization, thus forming an excellent centre of synergy in research, innovation and technology in the area of functional materials. This network offers a complete training in the synthesis and characterization of new spin crossover materials for various applications. 

http://amnol.usv.ro/pagina-05-4-b.php

 

Project: New porous coordinating polymers with variable dimensions organic ligands for gas storage
Project status: Ongoing

Project: POC E; P_37_707/31.08.2016
Acronym: POCPOLIG
Project coordinator: Dr. Vasile LOZAN / Project manager: Dr. Narcisa Laura MARANGOCI
Duration: 2016 - 2020

The objective of the project is to increase the capacity and quality of the research and innovation development activity by attracting specialists with advanced skills, opening a new research direction in the field of metal-organic networks (MOF) and diversifying the range of research services and transferring them to industrial partners, in order to stimulate the competitiveness of the Romanian scientific research at European level and of the national/regional economic competitiveness of the Institute and of the economic actors in the field of intelligent specialization of eco-nano-technologies and advanced materials.

http://pocpolig.icmpp.ro/

Project: Structural modification by plasma in liquids of different polyimide films. Mobility projects for young researchers in the diaspora (C. Miron- Japonia)
Project status: Ongoing

Code: PN-III-P1-1.1-MCT-2019-0066; Contract no. 7/8.08.2019
Project number: No. 525/21.01.2019
Project leader (Romania): I. Sava
Period: 2019-2020.

Bilateral Project between Shibaura Institute of Technology, Tokyo  - Japan and “Petru Poni” Institute of Macromolecular Chemistry, Iasi

Project: The engine of the hydrogen-based energy revolution. Fuel cells, on the road from research to production by minimizing technological barriers
Project status: Ongoing

Project: PN-III-25 PCCDI/2018
Acronym: ROFCC
Responsible partner (ICMPP): Dr. Valeria Harabagiu
Duration: 2018-2020
Buget: 709582 Lei

Fuel cell is unanimously considered the core of the hydrogen –based energy revolution. It promises to impact environmental and economic issues facing the world every day. Modern lifestyles, high prices for diminishing supplies of fossil fuels, and the environmental impact of energy production have all made alternative power generation technology like fuel cells a necessity. The proposed project is looking to find bridges between several scientific disciplines in order to reduce the main technological barriers which hinder the commercialization of PEM fuel cell at large scale.
Electrochemical energy conversion involves complex developments of materials: due to the close link between electricity flow and corrosion processes, morphological changes, building of resistive layers and exhaustion of catalytically active components, material development for enhanced lifetimes becomes the major challenge in fuel cell basic research and development. At the same time, the topics of low-cost materials and processing have to be additionally tackled in order to achieve acceptable market costs. Advances in the development of new catalysts, new bipolar plates, enhanced solid electrolyte are only few of the foreseen development within the project, based on joining the existing capabilities proved in other topics by the partners. The proposal covers entire range of research from applicative industrial research focused onto optimization materials/processes until experimental development for testing and validation of the production technology including a comprehensive cost analysis on life time.
By connecting the capabilities of several research partners in complementary topics, from physics, chemistry (especially electrochemistry but not only), mechanics, processes automation, etc. the project will bring the fuel cell development technology close to the market and ready to fulfill the requirements of the new hydrogen based chain energy system.

https://www.icsi.ro/rofcc-english-version/





© 2020   "Petru Poni" Institute of Macromolecular Chemistry, Iasi