INSTITUTUL DE CHIMIE MACROMOLECULARĂ PETRU PONI
(PETRU PONI INSTITUTE OF MACROMOLECULAR CHEMISTRY)
            


    

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Squalenoylation and micellar encapsulation as an effective approach for enhancing the biological properties of the antitumoral and antimicrobial drugs (Drug-ReSQue)
Project status: Ended
EN / RO
About Objectives Results Dissemination Team Contact

2024

Published/Sent for publication Papers

  1. B.-F. Craciun*, I. Rosca, D. Peptanariu, M. Pinteala. Enhancing the flucytosine antifungal efficiency by encapsulation into PEGylated squalene micellar nanocarrier. Bioconjugate Chemistry 2024, Under review, Manuscript ID: bc-2024-00237n. (IF = 4.7, Q2).

2023

Published/Sent for publication Papers

  1. B.-F. Craciun*, I.-A. Sandu, D. Peptanariu, M. Pinteala*. Novel Nanotherapeutic Systems Based on PEGylated Squalene Micelles for Enhanced In Vitro Activity of Methotrexate and Cytarabine. Polymers 2023, 15, 4225. https://doi.org/10.3390/polym15214225 (Gold OA) (IF = 5.0, Q1).

Conferences

  1. B.F. Craciun and M. Pinteala. Novel nanotherapeutic systems based on PEGylated squalene for improving the in vitro activity of commonly used antitumor drugs. 25th International Conference "Materials, Methods & Technologies 2023", Burgas, Bulgaria, August 17-20, 2023; Oral presentation.
  2. B.F. Craciun and M. Pinteala. PEGylated squalene-based nanotherapeutics: enhanced in vitro antitumor activity of commercial drugs. 15th Edition of the Conference ”New Trends in Chemistry Research”, Timisoara, Romania, September 21-22, 2023; Poster presentation.
  3. B.F. Craciun and M. Pinteala. Enhanced in vitro effectiveness of conventional drugs using PEGylated Squalene micelles as nanocarriers. 5th Edition of "Faculty of Chemistry Conference <5-MIT IasiCHEM 2023>", Iasi, Romania, October 26-27, 2023; Poster presentation.

2022

Conferences

  1. B.F. Craciun, D. Peptanariu, M. Pinteala. PEGylated squalene micelles as amphiphilic nano-carrier for in vitro enhanced delivery of methotrexate to MCF-7 tumoral cells. XXXVIth National Chemistry Conference (CNCHIM-2022), Calimanesti – Caciulata, Valcea, Romania, 04-07 October 2022; Poster presentation
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