Contract Authority: Executive Agency for Higher Education, Research, Development and Innovation Funding (UEFISDCI)
Project code: PN-IV-PCB-RO-MD-2024-0539
Acronym: MeMoMaR
Metabolic diseases are ranging from obesity, to rare inborn errors of metabolism, with others like cardiovascular diseases or cancer having characteristic abnormal metabolic patterns. The project will apply a NMR monitoring study for three metabolic conditions with high relevance for the Institute of Mother and Child from Chisinau: inborn errors of metabolism, obesity in childhood, and cervical cancer. Each of these diseases poses high challenges to our societies. Thus, advancing fast diagnosis and therapy assessment techniques is at forefront of current research worldwide. In terms of NMR spectroscopy, the Romanian group proposing the project is activating in the best-equipped laboratory in the country for solution-state NMR and medical diagnosis. The Moldavian team has advanced expertise in diagnosis and treatment of rare metabolic diseases, obese children and cervical cancer, with numerous enrolled patients. The proposed team include personnel belonging to the Reference Clinic for Inborn Errors of Metabolism, to the Coordination Center for Screening of Cervical Cancer, to the Reference Center in Colposcopy, as well as well-trained surgeons. The project is aiming to advance basic and applied knowledge in the targeted pathologies for better understanding the diseases and better monitoring the treatment efficacy. The main purpose is to disseminate fast the results as advanced research or case studies in order to speed up the benefits for the patients and society. |