O1. Obtaining and structural characterization of the components (collagen and pyrrole-sulfonamide hybrids) needed for proposed formulas. O2. In vitro evaluation of the cyto/hemocompatibility, antimicrobial, antibiofilm, antioxidant, immunomodulatory and pro-wound healing effects for both individual constituents and designed collagen-based formulas. O3. The optimization and verification of compositional consistency for the formulas exhibiting the most promising biological activity. O4. Project management and dissemination.