Scientific papers - Metubin Project

1. Copper(II) complexes with isomeric morpholine-substituted 2‑formylpyridine thiosemicarbazone hybrids as potential anticancer drugs inhibiting both ribonucleotide reductase and tubulin polymerization: The morpholine position matters,
M.N.M. Milunovic, K. Ohui, I. Besleaga, T.V. Petrasheuskaya, O. Domotor, É.A. Enyedy,* D. Darvasiova, P. Rapta, Z. Barbierikova, D. Vegh, S. Toth, J. Toth, N. Kucsma, G. Szakacs,* A. Popović-Bijelić, A. Zafar, J. Reynisson, A.D. Shutalev, R. Bai, E. Hamel, V.B. Arion*,
J. Med. Chem. 2024, 67, 9069−9090,
- https://doi.org/10.1021/acs.jmedchem.4c00259.

2. Are the metal identity and stoichiometry of metal complexes important for colchicine site binding and inhibition of tubulin polymerization?,
I. Besleaga, R. Raptová, A.-C. Stoica, M.N.M. Milunovic, M. Zalibera, R. Bai, N. Igaz, J. Reynisson, M. Kiricsi, É.A. Enyedy, P. Rapta, E. Hamel, V.B. Arion
Dalton Trans., 2024, 53, 12349,
- https://doi.org/10.1039/d4dt01469c.

3. Synthesis, X-ray and antibacterial activity of new copper(II) thiosemicarbazone complexes derived from 4-formyl-3-hydroxy-2-naphthoic acid,
N. Terenti, A. Lazarescu, S. Shova, P. Bourosh, N. Nedelko, A. Ślawska-Waniewska, E. Zariciuc, V. Lozan
Inorganica Chimica Acta, 571, 122216, 2024,
- https://doi.org/10.1016/j.ica.2024.122216.

4. Thermal actuators relying on elastomers-dispersed liquid crystals. From imines with supramolecular chirality and ferroelectricity to soft robots,
M. Damoc, C. Ursu, V. Tiron, G. Bulai, A.-C. Stoica, A.-M. Macsim, C.-D. Varganici, A. Bele, M. Dascalu, M. Cazacu
ACS Applied Materials & Interfaces, Manuscript ID: am-2024-11891n,
- under review.

,,The content of this material does not necessarily represent the official position of the European Union or the Government of Romania."
The project leading to this application has received funding from the Ministry of Research, Innovation and Digitization, project no.
PNRR-III-C9-2022-I8-201, contract no. 760082/23.05.2023, within the National Recovery and Resilience Plan.
,,PNRR. Finance by European Union-NextGenerationEU”
https://mfe.gov.ro/pnrr                                                                                https://www.facebook.com/PNRROficial