Scientific papers - Metubin Project

1. Copper(II) complexes with isomeric morpholine-substituted 2‑formylpyridine thiosemicarbazone hybrids as potential anticancer drugs inhibiting both ribonucleotide reductase and tubulin polymerization: The morpholine position matters,
M.N.M. Milunovic, K. Ohui, I. Besleaga, T.V. Petrasheuskaya, O. Domotor, É.A. Enyedy,* D. Darvasiova, P. Rapta, Z. Barbierikova, D. Vegh, S. Toth, J. Toth, N. Kucsma, G. Szakacs,* A. Popović-Bijelić, A. Zafar, J. Reynisson, A.D. Shutalev, R. Bai, E. Hamel, V.B. Arion*,
J. Med. Chem. 2024, 67, 9069−9090,
- https://doi.org/10.1021/acs.jmedchem.4c00259.

2. Are the metal identity and stoichiometry of metal complexes important for colchicine site binding and inhibition of tubulin polymerization?,
I. Besleaga, R. Raptová, A.-C. Stoica, M.N.M. Milunovic, M. Zalibera, R. Bai, N. Igaz, J. Reynisson, M. Kiricsi, É.A. Enyedy, P. Rapta, E. Hamel, V.B. Arion,
Dalton Trans., 2024, 53, 12349,
- https://doi.org/10.1039/d4dt01469c.

3. Synthesis, X-ray and antibacterial activity of new copper(II) thiosemicarbazone complexes derived from 4-formyl-3-hydroxy-2-naphthoic acid,
N. Terenti, A. Lazarescu, S. Shova, P. Bourosh, N. Nedelko, A. Ślawska-Waniewska, E. Zariciuc, V. Lozan
Inorganica Chimica Acta, 571, 122216, 2024,
- https://doi.org/10.1016/j.ica.2024.122216.

4. Thermal actuators relying on elastomers-dispersed liquid crystals. From imines with supramolecular chirality and ferroelectricity to soft robots,
M. Damoc, C. Ursu, V. Tiron, G. Bulai, A.-C. Stoica, A.-M. Macsim, C.-D. Varganici, A. Bele, M. Dascalu, M. Cazacu,
ACS Applied Materials & Interfaces, 17, 4185−4198, 2025,
- https://doi.org/10.1021/acsami.4c18088.

5. Physical properties and cytotoxicity of the Cu(II) and Zn(II) complexes with TMS-substituted indolo[2,3-c]quinoline-derived Schiff base,
C. Wittmann, I. Besleaga, S. Mahmoudi, O. Palamarciuc, M. Balan-Porcarasu, M. Dascalu, S. Shova, M. Cazacu, M. Kiricsi, N. Igaz, O. Dömötör, E. Enyedy, D. Dvoranová, P.Rapta, V. Arion,
Dalton Trans., 54, 7882-7898, 2025,
- https://doi.org/10.1039/D5DT00314H.

6. Paradigm shift in silicon-oxygen bonding: A novel disiloxane with linear geometry,
M. Damoc, A.-C. Stoica, M. Dascalu, S. Shova, M. Cazacu,
Revue Roumaine de Chimie – 2025 accepted,

7. 1D coordination polymers of Zn, Cu, and Co with 1,3-bis(cyanopropyl) tetramethyldisiloxane: Synthesis, structure, and moisture behavior,
A.-C. Stoica, M. Dascalu, S. Shova, M. Cazacu,
Revue Roumaine de Chimie – 2025 accepted,

8. Permethylated silicon: a structural motif with a critical role in shaping the properties of organic–inorganic compounds,
M. Cazacu, M. Damoc, A.C. Stoica, G.-O. Turcan-Trofin, M. Dascalu,
J Inorg Organomet Polym 2025. ,
- https://doi.org/10.1007/s10904-025-03868-4.

9. Siloxane-spaced salen-type Schiff base cobalt complex. Experimental and docking analysis—adual approach for evaluating anticancer efficacy,
M. Damoc, A.-C. Stoica, M.-F. Zaltariov, D. Peptanariu, M. Dascalu, M.Cazacu,
R. Soc. Open Sci. 12, 250279, 2025.,
- https://doi.org/10.1098/rsos.250279.

10. Copper(II) complex with a redox noninnocent Schiff base bearing a tetraphenyldisiloxane unit: synthesis, structure and catalytic oxidation of cyclohexane,
C. Wittmann, O. Palamarciuc, M. Dascalu, M. Cazacu, D. Nesterov, A. Pombeiro, P. Rapta, V. Arion,
Dalton Transactions, 54, 10984, 2025,
- https://doi.org/10.1039/d5dt01028d.

,,The content of this material does not necessarily represent the official position of the European Union or the Government of Romania."
The project leading to this application has received funding from the Ministry of Research, Innovation and Digitization, project no.
PNRR-III-C9-2022-I8-201, contract no. 760082/23.05.2023, within the National Recovery and Resilience Plan.
,,PNRR. Finance by European Union-NextGenerationEU”
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